"Tea Might Protect Transplanted Livers"
An antioxidant found in green tea may help protect patients recovering
from liver transplant, suggests a study in mice.
Restrictions in blood flow, or ischemia, can lead to complications
following liver transplantation in humans, particularly if the liver
is fatty, as it can be in obese individuals.
But a natural antioxidant found in green tea may protect transplanted
organs from ischemia-linked damage, according to researchers at the
Medical University of South Carolina, in Charleston.
A previous study found the simple act of rinsing fatty livers in a
solution containing green tea extract helped prevent transplant
failure.
In their study, the Charleston team gave mice doses of EGCG, the major
antioxidant flavonoid found in green tea. They then performed
surgeries resulting in ischemia that threatened to injure the rodents'
livers.
Mice receiving the green tea derivative showed a 100 percent
post-surgery survival rate, compared to a 65 percent survival for
animals not receiving the compound. Tissue analysis showed that mice
receiving the tea extract experienced less liver cell death and
retained a higher percentage of viable tissue.
Further research suggests the green tea extract acts as an
antioxidant, protecting fatty livers from injury while reducing liver
fat content by about 55 percent.